Maverick™ Type 1 Diabetes (T1D) Assay
1 diabetes (T1D) is an autoimmune disorder in which pancreatic islet β cells
are destroyed leading to insulin insufficiency. Pancreatic islet autoantigens
associated with T1D play diverse roles in glucose metabolism (insulin,
proinsulin), metabolism of biogenic amines (glutamate decarboxylases, GAD65 and
GAD67) and packaging of secretory vesicles (phosphotyrosine phosphatase-related
proteins, IA-2 and Phogrin, and zinc transporter, ZnT8). While its causes are
not yet entirely understood, scientists believe that both genetic factors and
environmental triggers are involved.
The Genalyte Maverick™ Type 1 Diabetes (T1D) Assay is a semi-quantitative photonic ring immunoassay (PRI) designed to simultaneously detect:
- GAD65 (Glutamate Decarboxylases)
- GAD67 (Glutamate Decarboxylases)
- IA-2 (PTPRN, ICA512)
- Phogrin (PTPRN2, IA-2β)
- ZnT8 (Zinc Transporter 8, SLC30A8)
Using only 2μL of and requiring minimal hands on time, the Maverick™ Detection System analyzes each of the target antigens in the T1D assay kit individually and reports out semi-quantitative results in ≈ 15 minutes.
Click to download our Maverick T1D Assay Poster .