Qavi et al. describe a method using microring resonator sensors to detect Ebola virus (EBOV) soluble glycoprotein (sGP) in serum. sGP is a promising biomarker for the prognosis of EBOV infection and, coupled with this rapid detection method, could lead to a faster diagnosis.
Highlights
- sGP is a unique diagnostic marker of Ebola virus infection
- Microring resonators can detect EBOV and SUDV sGP at low ng/mL concentrations
- Our sandwich immunoassay design enables the detection of antigens from serum
- Multiplex chip has flexible design, technical replicates, and integrated controls