Publications - Genalyte

Cell Reports Methods, Rapid detection of an Ebola biomarker with optical microring resonators

by CellPress - Abraham Qavi | Jun 20, 2022 | Publications, Scientific Publications

Qavi et al. describe a method using microring resonator sensors to detect Ebola virus (EBOV) soluble glycoprotein (sGP) in serum. sGP is a promising biomarker for the prognosis of EBOV infection and, coupled with this rapid detection method, could lead to a faster...

6 month serologic response to the Pfizer-BioNTech COVID-19 vaccine among healthcare workers

by PLoS One - Jason Cham | Apr 18, 2022 | News, Publications, Scientific Publications

Jason Cham, Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing,# 1 , 2 Amitabh C. Pandey, Writing – review &...

Pre-COVID-19 Immunity to Common Cold Human Coronaviruses Induces a Recall-Type IgG Response to SARS-CoV-2 Antigens Without Cross-Neutralisation

by Frontiers in Immunology - Makoto Miyara | Feb 11, 2022 | News, Publications, Scientific Publications

The capacity of pre-existing immunity to human common coronaviruses (HCoV) to cross-protect against de novo COVID-19is yet unknown. In this work, we studied the sera of 175 COVID-19 patients, 76 healthy donors and 3 intravenous immunoglobulins (IVIG)...

BNT162b2 vaccine-induced humoral and cellular responses against SARS-CoV-2 variants in systemic lupus erythematosus

by The BMJ - Quentin Moyon | Oct 4, 2021 | 2021 News, Publications, Scientific Publications

Abstract Objectives Our aim was to evaluate systemic lupus erythematosus (SLE) disease activity and SARS-CoV-2-specific immune responses after BNT162b2 vaccination. Methods In this prospective study, disease activity and clinical assessments were recorded...

Target specific serologic analysis of COVID-19 convalescent plasma

by PLoS One - Sachie Ikegami | Apr 28, 2021 | 2021 News, Publications, Scientific Publications

Abstract This study compared the performance of four serology assays for Coronavirus Disease 2019 (COVID-19) and investigated whether COVID-19 disease history correlates with assay performance. Samples were tested at Northshore using the Elecsys Anti-SARS-CoV-2 (Roche...

IgA dominates the early neutralizing antibody response to SARS-CoV-2

by SCIENCE - Delphine Sterlin | Dec 7, 2020 | 2020 News, Publications, Scientific Publications

Abstract Humoral immune responses are typically characterized by primary IgM antibody responses followed by secondary antibody responses associated with immune memory and composed of IgG, IgA, and IgE. Here, we measured acute humoral responses to SARS-CoV-2, including...

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