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Anti-DNA:RNA Antibodies and Silicon Photonic Microring Resonator Arrays Enable the Ultrasensitive, Multiplexed Detection of microRNAs

by Abraham Qavi | Jun 29, 2011 | 2011 News, Publications, Scientific Publications

Abstract In this paper, we present a method for the ultrasensitive detection of microRNAs (miRNAs) utilizing an antibody that specifically recognizes DNA:RNA heteroduplexes, using a silicon photonic microring resonator array transduction platform. Microring resonator...

Multiplexed inkjet functionalization of silicon photonic biosensors

by James Kirk | Apr 7, 2011 | 2011 News, Publications, Scientific Publications

Abstract The transformative potential of silicon photonics for chip-scale biosensing is limited primarily by the inability to selectively functionalize and exploit the extraordinary density of integrated optical devices on this platform. Silicon biosensors, such as...

Multiplexed Evaluation of Capture Agent Binding Kinetics Using Arrays of Silicon Photonic Microring Resonators

by Ji-Yeon Byeon | Nov 18, 2010 | 2010 News, Publications, Scientific Publications

Abstract High affinity capture agents recognizing biomolecular targets are essential to the performance of many proteomic detection methods. Herein, we report the application of a label-free silicon photonic biomolecular analysis platform for simultaneously...
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